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Granzyme A Antibody (PA5-96539) in ICC/IF
Immunofluorescence analysis of Granzyme A in U2OS cells. Samples were incubated with Granzyme A Polyclonal antibody (Product # PA5-96539) using a dilution of 1:100. Blue: DAPI for nuclear staining.
产品信息
PA5-96539
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 29-262 of human GZMA (NP_0061352)
偶联物
Unconjugated
形式
Liquid
浓度
2.85 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2808341
产品详细信息
Positive Samples: Mouse spleen, Mouse thymus, Rat intestine, Rat spleen; Cellular Location: Cytoplasmic granule
Immunogen sequence: IIGGNEVTPH SRPYMVLLSL DRKTICAGAL IAKDWVLTAA HCNLNKRSQV ILGAHSITRE EPTKQIMLVK KEFPYPCYDP ATREGDLKLL QLMEKAKINK YVTILHLPKK GDDVKPGTMC QVAGWGRTHN SASWSDTLRE VNITIIDRKV CNDRNHYNFN PVIGMNMVCA GSLRGGRDSC NGDSGSPLLC EGVFRGVTSF GLENKCGDPR GPGVYILLSK KHLNWIIMTI KGAV
靶标信息
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Autocrine thymic lymphoma granzyme-like serine protease; BLT esterase; CTL tryptase; CTLA-3; Cytotoxic T-lymphocyte proteinase 1; Cytotoxic T-lymphocyte-associated serine esterase-3; Fragmentin-1; granzyme 1; Granzyme A; Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease); granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3); Granzyme-1; H factor; Hanukah factor; Hanukah factor serine protease); Hanukkah factor; HF; serine esterase 1; T cell-specific serine protease 1; TSP-1
基因别名: AW494114; Ctla-3; CTLA3; GZMA; Hf; HFSP; Mtsp-1; SE1; TSP-1; TSP1
UniProt ID: (Human) P12544, (Mouse) P11032
Entrez Gene ID: (Human) 3001, (Rat) 266708, (Mouse) 14938
