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IGFBP2 Antibody (702196) in WB
Western blot analysis was performed on Whole cell extracts (30 µg lysate) of T-47D (Lane 1), T-47D (Condition Media) (Lane 2), PC-3 (Lane 3), PC-3 (Condition Media) (Lane 4), A549 (Lane 5) and A549 (Condition Media) (Lane 6). The blots were probed with Anti-IGFBP2 Recombinant Rabbit Monoclonal Antibody (Product # 702196, 1-2 µg/mL) and detected by chemiluminescence using Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, HRP conjugate (Product # A27036, 0.4 µg/mL, 1:2500 dilution). A 50 kDa Glycosylated and 35 kDa band for... View More
产品信息
702196
产品规格
宿主/亚型
Rabbit
/ IgG
Expression System
Expi293
分类
Recombinant Monoclonal
类型
Antibody
克隆号
1H2L9
抗原
Protein corresponding to Human IGFBP2 (aa 130-325)
偶联物
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2633066
产品详细信息
This antibody is predicted to react with Monkey, Bovine, Pig, Sheep and Goat
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
IGFBP2 (insulin-like growth factor binding protein 2) is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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