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Immunogen sequence: CSQGRCENT EGSFLCICPA GFMASEEGTN CIDVDECLRP DVCGEGHCVN TVGAFRCEYC DSGYRMTQRG RCEDIDECLN PSTCPDEQCV NSPGSYQCVP CTEGFRGWNG QCLDVDECLE PNVCANGDCS NLEGSYMCSC H (600-739 aa encoded by BC130289)
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins. The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Latent-transforming growth factor beta-binding protein 1; LTBP-1; MGC163161; TGF-beta1-BP-1; Transforming growth factor beta-1-binding protein 1
基因别名: LTBP1
UniProt ID: (Human) A1L3V1
Entrez Gene ID: (Human) 4052