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MAST4 Antibody (PA5-51407) in ICC/IF
Immunofluorecent analysis of MAST4 in human cell line A-431 using MAST4 Polyclonal Antibody (Product # PA5-51407). Staining shows localization to nucleoplasm and cytosol.
产品信息
PA5-51407
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human MAST4. Recombinant protein control fragment (Product #RP-93710).
偶联物
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2643777
产品详细信息
Immunogen sequence: PEKQESHQKS HGPGSDLENF ALFKLEEREK KVYPKAVERS STFENKASMQ EAPPLGSLLK DALHKQASVR ASEGAMSDGP VPAEHRQGGG DFRRAPAPGT LQDGLCHS
Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 60%.
靶标信息
The phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine/threonine(Ser/Thr) protein kinases. MAST4 (microtubule associated serine/threonine kinase family member 4), also known as KIAA0303, is a 2,626 amino acid protein that localizes to the cytoplasm and contains one protein kinase domain, as well as one PDZ domain and one AGC-kinase C-terminal domain. Expressed at high levels in most adult tissues, including testis, colon and small intestine, MAST4 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins. Multiple isoforms of MAST4 exist due to alternative splicing events.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Microtubule-associated serine/threonine-protein kinase 4
基因别名: KIAA0303; MAST4
UniProt ID: (Human) O15021
Entrez Gene ID: (Human) 375449
