Search Thermo Fisher Scientific
PA1-4135 detects Patched 2 (PTCH2) in human and mouse samples.
PA1-4135 has been successfully used in Western blot procedures. By Western blot this antibody detects a ~158 kDa protein representing PTCH2 in fetal brain lysate.
The PA1-4135 immunogen is a synthetic peptide corresponding to residues G(226) P F A S L E G F R(235) of human PTCH2.
Mutations of the human Patched tumor suppressor gene (PTCH) have been identified in individuals with the nevoid basal cell carcinoma syndrome (NBCCS) as well as in sporadic basal cell carcinomas and medulloblastomas. PTCH2 has a frameshift mutation resulting in a truncated PTCH2 protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: patched homolog 2; Protein patched homolog 2; PTC2; RP11-269F19.8
基因别名: PTC2; PTCH2; UNQ560/PRO1121/PRO57079
UniProt ID: (Human) Q9Y6C5, (Mouse) O35595
Entrez Gene ID: (Human) 8643, (Mouse) 19207