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Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) Antibody (PA5-118672) in ICC/IF
Immunocytochemical analysis of Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) in HepG2 cells using a Phospho-FGFR1/FGFR2 (Tyr730, Tyr733) polyclonal antibody (Product # PA5-118672). The samples were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjug... View More
产品信息
PA5-118672
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human FGFR1/2 around the phosphorylation site of Tyr730/733.
偶联物
Unconjugated
形式
Liquid
浓度
1 mg/mL
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2903172
靶标信息
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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