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产品信息
12549-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RGS17 Fusion Protein Ag3399 (1-210 aa encoded by BC013117)
偶联物
Unconjugated
形式
Liquid
浓度
0.43 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MRKRQQSQN EGTPAVSQAP GNQRPNNTCC FCWCCCCSCS CLTVRNEERG ENAGRPTHTT KMESIQVLEE CQNPTAEEVL SWSQNFDKMM KAPAGRNLFR EFLRTEYSEE NLLFWLACED LKKEQNKKVI EEKARMIYED YISILSPKEV SLDSRVREVI NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE S (1-210 aa encoded by BC013117)
靶标信息
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Regulator of G-protein signaling 17; regulator of G-protein signaling Z2; Regulator of Gz-selective protein signaling 2; RGS17
基因别名: 6430507P11Rik; hRGS17; RGS-17; RGS17; RGSZ2
UniProt ID: (Human) Q9UGC6, (Mouse) Q9QZB0
Entrez Gene ID: (Human) 26575, (Mouse) 56533
