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TARC Antibody (PA5-116367) in WB
Western Blot analysis of TARC using the TARC Polyclonal Antibody (Product # PA5-116367) at a 1:2000 dilution. Lane 1: human spleen lysates, Lane 2: human skeletal muscle lysates, Lane 3: human lung lysates. Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1:10,000 dilution. Predicted band size : 11 kDa. Blocking/Dilution buffer: 5% NFDM/TBST.
产品信息
PA5-116367
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
recombinant protein of human CCL17
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2901001
靶标信息
TARC ligand (CCL17) belongs to the CC chemokine family. It is a small cytokine and the gene is located on q arm of chromosome 16, in humans, along with other chemokines. TARC specifically binds to T-cells and interacts with chemokine receptors CCR4 and CCR8. It plays an important role in T cell development in thymus as well as in trafficking and activation of mature T cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C-C motif chemokine; C-C motif chemokine 17; CC chemokine TARC; chemokine (C-C motif) ligand 17; small inducible cytokine subfamily A (Cys-Cys), member 17; Small-inducible cytokine A17; T cell-directed CC chemokine; Thymus and activation-regulated chemokine
基因别名: A-152E5.3; ABCD-2; CCL17; SCYA17; TARC
UniProt ID: (Human) Q92583
Entrez Gene ID: (Human) 6361
monocyte chemotaxis
chemotaxis
inflammatory response
G-protein coupled receptor signaling pathway
cell-cell signaling
multicellular organism development
neutrophil chemotaxis
positive regulation of GTPase activity
negative regulation of myoblast differentiation
lymphocyte chemotaxis
chemokine-mediated signaling pathway
positive regulation of ERK1 and ERK2 cascade
cellular response to interferon-gamma
cellular response to interleukin-1
cellular response to tumor necrosis factor
