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The Human Monocyte-specific Chemokine 3 (CCL7)(Hu MCP-3) ELISA quantitates Hu MCP-3 in human serum, plasma, buffered solution, or cell culture medium. The assay will exclusively recognize both natural and recombinant Hu MCP-3.
原理方法
The Human MCP-3 solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen.
严格验证
Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.
This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
基因别名 : CCL7, FIC, MARC, MCP-3, MCP3, NC28, SCYA6, SCYA7
基因ID : (Human) 6354
基因符号 : CCL7
蛋白别名 : C-C motif chemokine 7, chemokine (C-C motif) ligand 7, H-MCP-3, MGC138463, MGC138465, RP23-350G1.4, MCP-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, small inducible cytokine A7 (monocyte chemotactic protein 3), Small-inducible cytokine A7
UniProt ID (Human) P80098