Search Thermo Fisher Scientific
This peptide corresponds to 14 amino acids near the carboxy terminus of human TRPC3.
PEP-0394 can be used as a blocking peptide with polyclonal antibody PA5-20258.
The mammalian transient receptor potential (TRP) superfamily can be divided into three major families including the "canonical TRP" (TRPC) family. The seven members of this family share the activation through PLC-coupled receptors and have been suggested to be components of receptor-regulated cation channels in different cell types. Furthermore, the members of the TRPC3/6/7 subfamily can be activated by diacylglycerol analogs, suggesting a possible mechanism of activation of these channels by PLC-coupled receptors. TRPC3 encodes a Ca2+-permeant channel that is agonist-activated but not store-operated or directly receptor-activated. TRPC3 physically interacts with TRPC6 and TRPC7 and forms functional tetrameric channels.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hTrp-3; hTrp3; Short transient receptor potential channel 3; transient receptor potential cation channel subfamily C member 3 variant c; transient receptor potential cation channel, subfamily C, member 3; Transient receptor protein 3; TRP-3; TrpC3
基因别名: SCA41; TRP3; TRPC3
UniProt ID: (Human) Q13507
Entrez Gene ID: (Human) 7222