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5-Formylcytosine (5-fC) Antibody (MA5-44549) in ELISA
ELISA analysis of DNA using 5-Formylcytosine (5-fC) Recombinant Monoclonal antibody (Product # MA5-44549) ata dilution of 1 µg/mL. The plate was coated with different concentrations of linear denatured DNA (426 bp) containing either normal cytosines (unmodified), 5-methylcytosines (5-mC), 5-hydroxymethylcytosines (5-hmC), 5-carboxylcytosines (5-caC), or 5-formylcytosines (5-fC).
产品信息
MA5-44549
产品规格
种属反应
Chemical
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
RM477
抗原
KLH-conjugated 5-Formylcytosines.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS with 1% BSA, 50% glycerol
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2926679
产品详细信息
This antibody reacts to dTyr alpha Tubulin
靶标信息
5-formylcytosine is an oxidized derivative of 5-methylcytosine, a type of DNA methylation. 5-formylcytosine is a nucleobase analogue with a cytosine that possesses a hydrogen at position 5 that has been replaced by a formyl group. 5-methylcytosine is oxidized to 5-hydroxymethylcytosine which is then oxidized to 5-formylcytosine and later to 5-carboxylcytosine. These oxidations are catalyzed by the Ten-Eleven Translocation (TET) enzyme family. 5-formylcytosine has been shown to determine nucleosome organization and plays a role in regulating transcription.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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