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Reconstitution: 1 X 25 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C, protected from the light, for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 X g 5 min).
SR-5B, also designated 5-hydroxytryptamine (serotonin) receptor 5B (5-HT5B) and G protein-coupled receptor 134 (GPR134), is a receptor for the monoamine ligand serotonin (5-hydroxytryptamine, 5-HT). Serotonin is a neurotransmitter derived from serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin actions are mediated by receptors that influence the biochemistry of depression, anxiety, sexuality and appetite. Rat SR-5B is present in serotonergic neurons in dorsal raphe (DR) and central superior nucleus (CS, median raphe nucleus). DR cell bodies showing SR-5B mRNA expression are abundant in the medial portions of the nucleus. CS coexpression of SR-5B receptor mRNA with serotonin transporter mRNA is high in the intermediate portions of the nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5-HT-5B; 5-HT5B; 5-hydroxytryptamine receptor 5B; MR22; protein-tyrosine-phosphatase (EC 3.1.3.48) Ly-5 precursor (B-cell variant); Serotonin receptor 5B
基因别名: 5-Ht5b; 5Ht5b; Htr5b; REC17
UniProt ID: (Rat) P35365
Entrez Gene ID: (Mouse) 15564, (Rat) 79247
分子生物学功能: G-protein coupled receptor