Bioss

A2AR/Adenosine A2a receptor Polyclonal Antibody

查看其他19个ADORA2A抗体

抗体检测数据 (2)

A2AR/Adenosine A2a receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))

A2AR/Adenosine A2a receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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A2AR/Adenosine A2a receptor Antibody (BS-1456R) in IHC (P)

Formalin-fixed and paraffin embedded mouse brain labeled with Anti-A2AR/Adenosine A2a Polyclonal Antibody, Unconjugated (bs-3927R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

A2AR/Adenosine A2a receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P))

A2AR/Adenosine A2a receptor Antibody in Western Blot (WB)

Product Image Gallery

A2AR/Adenosine A2a receptor Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Formalin-fixed and paraffin embedded mouse brain labeled with Anti-A2AR/Adenosine A2a Polyclonal Antibody, Unconjugated (bs-3927R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.

A2AR/Adenosine A2a receptor Antibody in Western Blot (WB) — Lane 1: rat heart lysates Lane 2: rat brain lysates probed with Anti A2AR/Adenosine A2a receptor Polyclonal Antibody, Unconjugated (bs-1456R) at 1:200 in 4°C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90 min in 37°C. Predicted band 64 kD. Observed band size: 64 kD.

产品信息

BS-1456R

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:200

-

免疫组化（石蜡） (IHC (P))

1:200

-

酶联免疫吸附实验 (ELISA)

1:500-1:1,000

-

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

KLH conjugated synthetic peptide derived from human A2a receptor, amino acids 165-300.

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

纯化类型

Protein A

保存液

0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol

内含物

0.02% ProClin 300

保存条件

-20°C

运输条件

Ambient (domestic); Wet ice (international)

靶标信息

ADORA2A is a protein which is one of several receptor subtypes for adenosine. The activity of the encoded protein, a G-protein coupled receptor family member, is mediated by G proteins which activate adenylyl cyclase. This protein is abundant in basal ganglia, vasculature and platelets and it is a major target of caffeine.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: A2a receptor; Adenosine A2a-receptor; Adenosine receptor A2a; adenosine receptor subtype A2a; hA2aR

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基因别名: A2AAR; A2aR; AA2AR; ADENO; ADORA2; ADORA2A; Adora2l1; RDC8

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UniProt ID: (Human) P29274, (Mouse) Q60613, (Rat) P30543

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Entrez Gene ID: (Human) 135, (Mouse) 11540, (Rat) 25369

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G-protein coupled adenosine receptor activity protein binding enzyme binding identical protein binding signal transducer activity G-protein coupled receptor activity type 5 metabotropic glutamate receptor binding protein heterodimerization activity alpha-actinin binding G-protein coupled receptor

参与通路

adenosine receptor signaling pathway cAMP biosynthetic process phagocytosis apoptotic process inflammatory response cellular defense response adenylate cyclase-modulating G-protein coupled receptor signaling pathway cell-cell signaling central nervous system development blood coagulation sensory perception blood circulation positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway cellular protein metabolic process synaptic transmission, dopaminergic response to amphetamine regulation of transcription, DNA-templated negative regulation of protein kinase activity signal transduction G-protein coupled receptor signaling pathway adenylate cyclase-activating G-protein coupled receptor signaling pathway protein kinase C-activating G-protein coupled receptor signaling pathway synaptic transmission, cholinergic locomotory behavior negative regulation of cell proliferation positive regulation of glutamate secretion positive regulation of acetylcholine secretion, neurotransmission regulation of norepinephrine secretion positive regulation of cAMP biosynthetic process response to caffeine positive regulation of synaptic transmission, GABAergic synaptic transmission, glutamatergic positive regulation of urine volume positive regulation of renal sodium excretion negative regulation of locomotion vasodilation eating behavior negative regulation of vascular permeability negative regulation of cysteine-type endopeptidase activity involved in apoptotic process response to alkaloid negative regulation of neuron apoptotic process positive regulation of circadian sleep/wake cycle, sleep negative regulation of alpha-beta T cell activation astrocyte activation regulation of synaptic plasticity neuron projection morphogenesis positive regulation of protein secretion negative regulation of inflammatory response regulation of mitochondrial membrane potential membrane depolarization regulation of calcium ion transport positive regulation of synaptic transmission, glutamatergic excitatory postsynaptic potential inhibitory postsynaptic potential prepulse inhibition positive regulation of apoptotic signaling pathway response to drug