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Invitrogen
A2M Polyclonal Antibody
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产品信息
PA1-32980
应用
建议稀释比
已发表文章
产品规格
已发表种属
Human
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Human alpha 2 -macroglobulin purified from plasma
偶联物
形式
Liquid
浓度
18.6 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-32980 detects A2M from canine, porcine, guinea pig, human, bovine, rabbit, feline, and horse samples.
PA1-32980 has been successfully used in IDF, IE and RIA applications.
The PA1-32980 immunogen is: Human alpha 2 -macroglobulin purified from plasma
Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
靶标信息
Alpha 2-Macroglobulin (a2M), is a approximately 720-kDa homotetrameric glycoprotein composed of four identical approximately 180 kDa subunits. aAlpha 2M shares with other alpha-macroglobulins, like the complement components C3 and C4 and the pregnancy zone protein PZP, an extraordinary binding capacity for a variety of ligands. This allows the alpha-macroglobulins to serve as humoral defense barriers against foreign peptides in the plasma. Alpha 2M interacts and captures virtually any proteinase, often referred to as a panprotease inhibitor. In the brain of Alzheimer's disease (AD) patients, Alpha 2M also has been localized to diffuse amyloid plaques, supporting an important role for alpha 2M in AD etiopathology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
