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Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MPDNIEESWK IMALDAIAKT CTFTAMCFEN MRIMRYEEFI SMIFRLDYTQ PLSDEYITVT DTTFVDIPVR LYLPKRKSET RRRAVIYFHG GGFCFGSSKQ RAFDFLNRWT ANTLDAVVVG VDYRLAPQHH FPAQFEDGLA AVKFFLLEKI LTKYGVDPTR ICISGDSSGG NLATAVTQQV QNDAEIKHKI KMQVLLYPGL QITDSYLPSH RENEHGIVLT RDVAIKLVSL YFTKDEALPW AMRRNQHMPL ESRHLFKFVN WSILLPEKYR KDYVYTEPIL GGLSYSLPGL TDSRALPLLA NDSQLQNLPL TYILTCQHDL LRDDGLMYVT RLRNVGVQVV HEHIEDGIHG ALSFMTSPFY LRLGLRIRDM YVSWLDKNL
AADAC is a 45 kDa membrane-associated hydrolase highly expressed in the human liver that has been implicated in the hydrolysis of arylacetamide xenobiotics including flutamide and phenacetin.556-560AADAC is highly homologous to several related lipases, AADACL1, 2, and 4, the latter two of which remain completely unannotated. Overexpression of AADAC in a rat hepatoma cell line produces changes in cellular TG levels, apoplipoprotein B secretion, and fatty acid oxidation, but the mechanism for these effects remains unclear. 561 Candidate endogenous substrates, selective inhibitors, or knockout mice have not, to our knowledge, been described for AADAC or the related enzymes AADACL2 and AADACL4.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADCL2; Arylacetamide deacetylase-like 2; MGC72001
基因别名: AADACL2
UniProt ID: (Human) Q6P093
Entrez Gene ID: (Human) 344752
分子生物学功能:
deacetylase