Proteintech

ABCG5 Polyclonal Antibody

ABCG5 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

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ABCG5 Antibody (27722-1-AP) in IHC (P)

Immunohistochemistry of paraffin-embedded human liver tissue slide using 27722-1-AP (ABCG5 antibody) at dilution of 1:200 (under 40x lens).

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产品信息

27722-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:2,000

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免疫组化（石蜡） (IHC (P))

1:50-1:500

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ABCG5 Fusion Protein Ag26844 (1-85 aa encoded by NM_022436)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.3 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

Immunogen sequence: MGDLSSLTP GGSMGLQVNR GSQSSLEGAP ATAPEPHSLG ILHASYSVSH RVRPWWDITS CRQQWTRQIL KDVSLYVESG QIMCIL (1-85 aa encoded by NM _022436)

靶标信息

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: ATP-binding cassette sub-family G (WHITE) member 5 (sterolin 1); ATP-binding cassette sub-family G member 5; ATP-binding cassette, sub-family G (WHITE), member 5; ATP-binding cassette, sub-family G (WHITE), member 5 (sterolin 1); ATP-binding cassette, subfamily G, member 5; sterolin 1; Sterolin-1

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基因别名: ABCG5; AW112016; cmp; sterolin-1; STSL; trac

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UniProt ID: (Human) Q9H222, (Rat) Q99PE7, (Mouse) Q99PE8

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Entrez Gene ID: (Human) 64240, (Rat) 114628, (Mouse) 27409

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功能

protein binding ATP binding ATPase activity cholesterol transporter activity ATPase activity, coupled to transmembrane movement of substances protein heterodimerization activity nucleotide binding ATP-binding cassette (ABC) transporter primary active transporter transporter

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