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ABHD3 Antibody (MA5-44987) in WB
Western blot analysis of Abhydrolase_3 domain-containing protein in recombinant protein. Proteins were transferred to a PVDF membrane and blocked with 5% BSA in PBS for 1 hour at room temperature. Samples were incubated in Abhydrolase_3 domain-containing protein Monoclonal antibody (Product # MA5-44987) using a dilution of 1:500 in 5% BSA at room temperature for 2 hours followed by Goat Anti-Mouse IgG - HRP secondary antibody at a dilution of 1:20,000 for 1 hour at room temperature.
产品信息
MA5-44987
产品规格
种属反应
Plant
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
A5D4
抗原
Recombinant full length protein within Camellia.
偶联物
形式
Liquid
浓度
2 mg/mL
纯化类型
Protein G
保存液
TBS, pH 7.4, with 0.2% BSA, 50% glycerol
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2931443
靶标信息
The α/β hydrolase superfamily comprise diverse members that are involved in important biochemical processes and related to various diseases. They have unrelated sequences, various substrates, and different kinds of catalytic activities, yet they share the same canonical α/β hydrolase fold, which consists of an eight stranded parallel α/β structure. They are also characterized by a catalytic triad composed of a histidine, an acid and a nucleophile. Members of this superfamily are often drug targets for treating diseases, such as diabetes, Alzheimer's disease, obesity and blood clotting disorders. The α/β hydrolase domain containing (ABHD) gene subfamily is comprised of 15 mostlyuncharacterized members, most of which utilize a serine nucleophile to form the G-X-S-X-G nucleophile elbow. ABHD1 plays a role in metabolizing smoking xenobiotics. ABHD2 participates in the development of atherosclerosis. ABHD3 is a 409 amino acid single-pass type II membrane protein. ABHD4 is involved in an alternative synthesis pathway of NAE (N-acyl ethanolamine). Mutations in ABHD5 contribute to Chanarin-Dorfman syndrome. ABDH6 may play a role in nervous system metabolism and signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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