Invitrogen

ACAA2 Polyclonal Antibody

高级验证

This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.

查看其他17个ACAA2抗体

说明书

实验方案

技术支持

说明书

实验方案

技术支持

抗体检测数据 (2)
高级验证 (1)

ACAA2 Antibody in Immunohistochemistry (IHC)

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ACAA2 Antibody (PA5-59942) in IHC

Immunohistochemical staining of ACAA2 in human kidney and pancreas tissues using ACAA2 Polyclonal Antibody (Product # PA5-59942). Corresponding ACAA2 RNA-seq data are presented for the same tissues.

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ACAA2 Antibody — Relative expression in different tissues in IHC: Detection of differential expression levels of ACAA2 demonstrates antibody specificity. Immunohistochemical analysis of ACAA2 using anti-ACAA2 Polyclonal Antibody (Product # PA5-59942), shows significant staining of ACAA2 in human kidney and shows minimal or weak staining in human pancreas tissues. The relative expression levels of ACAA2 within each tissue is shown using RNA-Seq. {RE}

产品信息

PA5-59942

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

免疫组化 (IHC)

1:20-1:50

免疫细胞化学 (ICC/IF)

0.25-2 µg/mL

产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human ACAA2. Recombinant protein control fragment (Product #RP-88974).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.05 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Wet ice

RRID

AB_2637576

产品详细信息

Immunogen sequence: LLRGVFVVAA KRTPFGAYGG LLKDFTATDL SEFAAKAALS AGKVSPETVD SVIMGNVLQS SSDAIYLARH VGLRVGIPKE TPALTINRLC GSGFQSIVNG CQEICVKEAE VVLCGGTESM SQAPYCVRNV RFGTKLGSDI KLEDSLW

Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.

靶标信息

ACAA2 (3-Ketoacyl-CoA thiolase) is an enzyme that in humans is encoded by the ACAA2 gene. Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; acetyl-Coenzyme A acyltransferase 2; acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase); Acyl-CoA hydrolase, mitochondrial; beta ketothiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; T1

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基因别名: 0610011L04Rik; ACAA2; AI255831; AI265397; D18Ertd240e; DSAEC

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UniProt ID: (Human) P42765, (Mouse) Q8BWT1, (Rat) P13437

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Entrez Gene ID: (Human) 10449, (Mouse) 52538, (Rat) 170465

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功能

acetyl-CoA C-acyltransferase activity protein binding poly(A) RNA binding catalytic activity transferase activity transferase activity, transferring acyl groups transferase activity, transferring acyl groups other than amino-acyl groups acyltransferase

参与通路

fatty acid metabolic process cholesterol biosynthetic process cellular response to hypoxia negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway negative regulation of mitochondrial membrane permeability involved in apoptotic process acetyl-CoA metabolic process lipid metabolic process fatty acid beta-oxidation metabolic process