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产品信息
MA5-42617
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
8H6H5
抗原
A synthetic peptide corresponding to a sequence within amino acids 298-397 of human ACAA2 (P42765).
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol, 0.05% BSA
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2911758
产品详细信息
Positive test controls include: HeLa, HepG2, A-549, Rat heart. The target is usually found in the following locations: Mitochondrion.
Immunogen sequence: PAISGALKKA GLSLKDMDLV EVNEAFAPQY LAVERSLDLD ISKTNVNGGA IALGHPLGGS GSRITAHLVH ELRRRGGKYA VGSACIGGGQ GIAVIIQSTA
靶标信息
ACAA2 (3-Ketoacyl-CoA thiolase) is an enzyme that in humans is encoded by the ACAA2 gene. Acetyl-Coenzyme A acyltransferase 2 is an acetyl-CoA C-acyltransferase enzyme. The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; acetyl-Coenzyme A acyltransferase 2; acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase); Acyl-CoA hydrolase, mitochondrial; beta ketothiolase; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; T1
基因别名: 0610011L04Rik; ACAA2; AI255831; AI265397; D18Ertd240e; DSAEC
UniProt ID: (Human) P42765, (Mouse) Q8BWT1, (Rat) P13437
Entrez Gene ID: (Human) 10449, (Mouse) 52538, (Rat) 170465
fatty acid metabolic process
cholesterol biosynthetic process
cellular response to hypoxia
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
negative regulation of mitochondrial membrane permeability involved in apoptotic process
acetyl-CoA metabolic process
lipid metabolic process
fatty acid beta-oxidation
metabolic process
