Product References
Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma.
International journal of biological sciences
Cai J,Chen T,Jiang Z,Yan J,Ye Z,Ruan Y,Tao L,Shen Z,Liang X,Wang Y,Xu J,Cai X
Tue May 09 00:00:00 UTC 2023
Bulk and single-cell transcriptome profiling reveal extracellular matrix mechanical regulation of lipid metabolism reprograming through YAP/TEAD4/ACADL axis in hepatocellular carcinoma.
International journal of biological sciences
Cai J,Chen T,Jiang Z,Yan J,Ye Z,Ruan Y,Tao L,Shen Z,Liang X,Wang Y,Xu J,Cai X
Tue May 09 00:00:00 UTC 2023
Klf4-Sirt3/Pparα-Lcad pathway contributes to high phosphate-induced lipid degradation.
Cell communication and signaling : CCS
Yu A,Xu Y,Hogstrand C,Zhao T,Tan XY,Wei X,Song YF,Luo Z
Mon Jan 09 00:00:00 UTC 2023
Novel treatment and insight for irradiation-induced injuries: Dibucaine ameliorates irradiation-induced testicular injury by inhibiting fatty acid oxidation in primary Leydig cells.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ran L,Chen Q,Lu X,Gao Z,Cui F,Liu X,Xue B
Tue Aug 01 00:00:00 UTC 2023
Suppression of fatty acid oxidation supports pancreatic cancer growth and survival under hypoxic conditions through autophagy induction.
Cancer gene therapy
Kim B,Gwak J,Kim M,Yang S,Hwang S,Shin S,Kim JH,Son J,Jeong SM
Thu Jun 01 00:00:00 UTC 2023
ACADL suppresses PD-L1 expression to prevent cancer immune evasion by targeting Hippo/YAP signaling in lung adenocarcinoma.
Medical oncology (Northwood, London, England)
Li L,Wang LL,Wang TL,Zheng FM
Fri Mar 17 00:00:00 UTC 2023
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction.
Scientific reports
Mushala BAS,Xie B,Sipula IJ,Stoner MW,Thapa D,Manning JR,Bugga P,Vandevender AM,Jurczak MJ,Scott I
Sat Apr 15 00:00:00 UTC 2023
NQO1/CPT1A promotes the progression of pancreatic adenocarcinoma via fatty acid oxidation.
Acta biochimica et biophysica Sinica
Xu R,Liu Y,Ma L,Sun Y,Liu H,Yang Y,Jin T,Yang D
Mon May 29 00:00:00 UTC 2023
ZLN005 Alleviates In Vivo and In Vitro Renal Fibrosis via PGC-1α-Mediated Mitochondrial Homeostasis.
Pharmaceuticals (Basel, Switzerland)
Zhu P,Ma H,Cui S,Zhou X,Xu W,Yu J,Li J
Thu Mar 31 00:00:00 UTC 2022
Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE-/- Mouse Model.
Cells
Längst N,Adler J,Kuret A,Peter A,Ruth P,Boldt K,Lukowski R
Sun Apr 17 00:00:00 UTC 2022
Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE-/- Mouse Model.
Cells
Längst N,Adler J,Kuret A,Peter A,Ruth P,Boldt K,Lukowski R
Sun Apr 17 00:00:00 UTC 2022
Nicotinamide Mononucleotide Administration Restores Redox Homeostasis via the Sirt3-Nrf2 Axis and Protects Aged Mice from Oxidative Stress-Induced Liver Injury.
Journal of proteome research
Luo C,Ding W,Yang C,Zhang W,Liu X,Deng H
Fri Jul 01 00:00:00 UTC 2022
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Frontiers in oncology
Guo D,Zhang X,Cui H,Yu D,Zhang H,Shi X,Pang C,Li J,Guo W,Zhang S
Sat Feb 19 00:00:00 UTC 2022
ACADL Functions as a Tumor Suppressor in Hepatocellular Carcinoma Metastasis by Inhibiting Matrix Metalloproteinase 14.
Frontiers in oncology
Guo D,Zhang X,Cui H,Yu D,Zhang H,Shi X,Pang C,Li J,Guo W,Zhang S
Sat Feb 19 00:00:00 UTC 2022
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
The Journal of physiology
Drake RR,Louey S,Thornburg KL
Tue Feb 01 00:00:00 UTC 2022
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Nano-micro letters
Kim D,Wu Y,Li Q,Oh YK
Mon Jan 04 00:00:00 UTC 2021
The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Frontiers in cell and developmental biology
Yang J,Zhang Y,Pan Y,Sun C,Liu Z,Liu N,Fu Y,Li X,Li Y,Kong J
Fri May 14 00:00:00 UTC 2021
NAD+ Repletion Reverses Heart Failure With Preserved Ejection Fraction.
Circulation research
Tong D,Schiattarella GG,Jiang N,Altamirano F,Szweda PA,Elnwasany A,Lee DI,Yoo H,Kass DA,Szweda LI,Lavandero S,Verdin E,Gillette TG,Hill JA
Fri May 28 00:00:00 UTC 2021
The role of SAMM50 in non-alcoholic fatty liver disease: from genetics to mechanisms.
FEBS open bio
Li Z,Shen W,Wu G,Qin C,Zhang Y,Wang Y,Song G,Xiao C,Zhang X,Deng G,Wang R,Wang X
Thu Jul 01 00:00:00 UTC 2021
Fatty Acids Inhibit LAMP2-Mediated Autophagy Flux via Activating ER Stress Pathway in Alcohol-Related Liver Disease.
Cellular and molecular gastroenterology and hepatology
Guo W,Zhong W,Hao L,Dong H,Sun X,Yue R,Li T,Zhou Z
Mon Mar 28 00:00:00 UTC 2022
Multi-Omics Analysis of Fatty Acid Metabolism in Thyroid Carcinoma.
Frontiers in oncology
Lu J,Zhang Y,Sun M,Ding C,Zhang L,Kong Y,Cai M,Miccoli P,Ma C,Yue X
Fri Apr 29 00:00:00 UTC 2022
Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis.
Cell death discovery
Ren M,Xu H,Xia H,Tang Q,Bi F
Sat May 29 00:00:00 UTC 2021
The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression.
Cells
Santos SS,Moreira JB,Costa M,Rodrigues RS,Sebastião AM,Xapelli S,Solá S
Wed Dec 29 00:00:00 UTC 2021
The Mitochondrial Antioxidant Sirtuin3 Cooperates with Lipid Metabolism to Safeguard Neurogenesis in Aging and Depression.
Cells
Santos SS,Moreira JB,Costa M,Rodrigues RS,Sebastião AM,Xapelli S,Solá S
Wed Dec 29 00:00:00 UTC 2021
Reprogramming of Lipid Metabolism as a New Driving Force Behind Tauroursodeoxycholic Acid-Induced Neural Stem Cell Proliferation.
Frontiers in cell and developmental biology
Fernandes MB,Costa M,Ribeiro MF,Siquenique S,Sá Santos S,Martins J,Coelho AV,Silva MFB,Rodrigues CMP,Solá S
Mon Sep 28 00:00:00 UTC 2020
Slc22a5 haploinsufficiency does not aggravate the phenotype of the long-chain acyl-CoA dehydrogenase KO mouse.
Journal of inherited metabolic disease
Ranea-Robles P,Yu C,van Vlies N,Vaz FM,Houten SM
Fri May 01 00:00:00 UTC 2020
Increased fatty acid oxidation enzyme activity in the hearts of mice fed a high fat diet does not correlate with improved cardiac contractile function.
Current research in physiology
Thapa D,Manning JR,Mushala BAS,Stoner MW,Zhang M,Scott I
Tue Dec 01 00:00:00 UTC 2020
Functional changes of the liver in the absence of growth hormone (GH) action - Proteomic and metabolomic insights from a GH receptor deficient pig model.
Molecular metabolism
Riedel EO,Hinrichs A,Kemter E,Dahlhoff M,Backman M,Rathkolb B,Prehn C,Adamski J,Renner S,Blutke A,de Angelis MH,Bidlingmaier M,Schopohl J,Arnold GJ,Fröhlich T,Wolf E
Mon Jun 01 00:00:00 UTC 2020
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
Bio-protocol
Lv T,Zhu S,Ma Y,Feng H,Wan Q
Sun Sep 20 00:00:00 UTC 2020
Immunoprecipitation of Acetyl-lysine And Western Blotting of Long-chain acyl-CoA Dehydrogenases and Beta-hydroxyacyl-CoA Dehydrogenase in Palmitic Acid Treated Human Renal Tubular Epithelial Cells.
Bio-protocol
Lv T,Zhu S,Ma Y,Feng H,Wan Q
Sun Sep 20 00:00:00 UTC 2020
Berberine alleviates nonalcoholic fatty liver induced by a high-fat diet in mice by activating SIRT3.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Xu X,Zhu XP,Bai JY,Xia P,Li Y,Lu Y,Li XY,Gao X
Sat Jun 01 00:00:00 UTC 2019
GCN5L1 controls renal lipotoxicity through regulating acetylation of fatty acid oxidation enzymes.
Journal of physiology and biochemistry
Lv T,Hu Y,Ma Y,Zhen J,Xin W,Wan Q
Fri Nov 01 00:00:00 UTC 2019
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 UTC 2018
Exogenous H2S switches cardiac energy substrate metabolism by regulating SIRT3 expression in db/db mice.
Journal of molecular medicine (Berlin, Germany)
Sun Y,Tian Z,Liu N,Zhang L,Gao Z,Sun X,Yu M,Wu J,Yang F,Zhao Y,Ren H,Chen H,Zhao D,Wang Y,Dong S,Xu C,Lu F,Zhang W
Sun Apr 01 00:00:00 UTC 2018
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
The Journal of biological chemistry
Thapa D,Wu K,Stoner MW,Xie B,Zhang M,Manning JR,Lu Z,Li JH,Chen Y,Gucek M,Playford MP,Mehta NN,Harmon D,O'Doherty RM,Jurczak MJ,Sack MN,Scott I
Fri Nov 16 00:00:00 UTC 2018
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
The Journal of biological chemistry
Thapa D,Wu K,Stoner MW,Xie B,Zhang M,Manning JR,Lu Z,Li JH,Chen Y,Gucek M,Playford MP,Mehta NN,Harmon D,O'Doherty RM,Jurczak MJ,Sack MN,Scott I
Fri Nov 16 00:00:00 UTC 2018
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Scientific reports
Zhang W,Zhong W,Sun Q,Sun X,Zhou Z
Thu Jan 11 00:00:00 UTC 2018
Adipose-specific lipin1 overexpression in mice protects against alcohol-induced liver injury.
Scientific reports
Zhang W,Zhong W,Sun Q,Sun X,Zhou Z
Thu Jan 11 00:00:00 UTC 2018
Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.
Diabetes
Ohashi N,Morino K,Ida S,Sekine O,Lemecha M,Kume S,Park SY,Choi CS,Ugi S,Maegawa H
Fri Sep 01 00:00:00 UTC 2017
Pivotal Role of O-GlcNAc Modification in Cold-Induced Thermogenesis by Brown Adipose Tissue Through Mitochondrial Biogenesis.
Diabetes
Ohashi N,Morino K,Ida S,Sekine O,Lemecha M,Kume S,Park SY,Choi CS,Ugi S,Maegawa H
Fri Sep 01 00:00:00 UTC 2017
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
American journal of physiology. Heart and circulatory physiology
Thapa D,Zhang M,Manning JR,Guimarães DA,Stoner MW,O'Doherty RM,Shiva S,Scott I
Tue Aug 01 00:00:00 UTC 2017
Acetylation of mitochondrial proteins by GCN5L1 promotes enhanced fatty acid oxidation in the heart.
American journal of physiology. Heart and circulatory physiology
Thapa D,Zhang M,Manning JR,Guimarães DA,Stoner MW,O'Doherty RM,Shiva S,Scott I
Tue Aug 01 00:00:00 UTC 2017
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Scientific reports
Wu L,Guo X,Lyu Y,Clarke SL,Lucas EA,Smith BJ,Hildebrand D,Wang W,Medeiros DM,Shen X,Lin D
Tue Nov 07 00:00:00 UTC 2017
Targeted Metabolomics Reveals Abnormal Hepatic Energy Metabolism by Depletion of β-Carotene Oxygenase 2 in Mice.
Scientific reports
Wu L,Guo X,Lyu Y,Clarke SL,Lucas EA,Smith BJ,Hildebrand D,Wang W,Medeiros DM,Shen X,Lin D
Tue Nov 07 00:00:00 UTC 2017
Identification of SPOP related metabolic pathways in prostate cancer.
Oncotarget
Yan M,Qi H,Li J,Ye G,Shao Y,Li T,Liu J,Piao HL,Xu G
Tue Nov 28 00:00:00 UTC 2017
Identification of SPOP related metabolic pathways in prostate cancer.
Oncotarget
Yan M,Qi H,Li J,Ye G,Shao Y,Li T,Liu J,Piao HL,Xu G
Tue Nov 28 00:00:00 UTC 2017
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Scientific reports
Zhang W,Zhong W,Sun Q,Sun X,Zhou Z
Mon Aug 21 00:00:00 UTC 2017
Hepatic overproduction of 13-HODE due to ALOX15 upregulation contributes to alcohol-induced liver injury in mice.
Scientific reports
Zhang W,Zhong W,Sun Q,Sun X,Zhou Z
Mon Aug 21 00:00:00 UTC 2017
Enzogenol improves diabetes-related metabolic change in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus.
The Journal of pharmacy and pharmacology
Bang CY,Choung SY
Sun Jun 01 00:00:00 UTC 2014
Enzogenol improves diabetes-related metabolic change in C57BL/KsJ-db/db mice, a model of type 2 diabetes mellitus.
The Journal of pharmacy and pharmacology
Bang CY,Choung SY
Sun Jun 01 00:00:00 UTC 2014
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Cell reports
Huang D,Li T,Li X,Zhang L,Sun L,He X,Zhong X,Jia D,Song L,Semenza GL,Gao P,Zhang H
Thu Sep 25 00:00:00 UTC 2014
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Cell reports
Huang D,Li T,Li X,Zhang L,Sun L,He X,Zhong X,Jia D,Song L,Semenza GL,Gao P,Zhang H
Thu Sep 25 00:00:00 UTC 2014
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Cell reports
Huang D,Li T,Li X,Zhang L,Sun L,He X,Zhong X,Jia D,Song L,Semenza GL,Gao P,Zhang H
Thu Sep 25 00:00:00 UTC 2014
HIF-1-mediated suppression of acyl-CoA dehydrogenases and fatty acid oxidation is critical for cancer progression.
Cell reports
Huang D,Li T,Li X,Zhang L,Sun L,He X,Zhong X,Jia D,Song L,Semenza GL,Gao P,Zhang H
Thu Sep 25 00:00:00 UTC 2014
Diet-sensitive sources of reactive oxygen species in liver mitochondria: role of very long chain acyl-CoA dehydrogenases.
PloS one
Cardoso AR,Kakimoto PA,Kowaltowski AJ
Tue Jun 17 00:00:00 UTC 2014
