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ACAT1 Antibody (PA5-89127) in IHC (P)
Immunohistochemistry analysis of ACAT1 in paraffin-embedded human liver cancer. Samples were incubated with ACAT1 Polyclonal antibody (Product # PA5-89127) using a dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7.2 before commencing with IHC staining protocol.
产品信息
PA5-89127
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-145 of human ACAT1 (NP_0000101)
偶联物
形式
Liquid
浓度
0.68 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2805372
产品详细信息
Immunogen sequence: MAVLAALLRS GARSRSPLLR RLVQEIRYVE RSYVSKPTLK EVVIVSATRT PIGSFLGSLS LLPATKLGSI AIQGAIEKAG IPKEEVKEAY MGNVLQGGEG QAPTRQAVLG AGLPISTPCT TINKVCASGM KAIMMASQSL MCGHQ; Positive Samples: SW620, Raji, H460, HepG2, Mouse liver, Mouse testis, Mouse small intestine; Cellular Location: Mitochondrion
靶标信息
ACAT-1 is a ~50 kDa protein that catalyzes the formation of intracellular cholesterol esters in various tissues, such as adult human liver, adrenal glands, macrophages, and kidneys.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acetoacetyl Coenzyme A thiolase; Acetoacetyl-CoA thiolase; acetyl-Co A acetyltransferase 1 mitochondrial; Acetyl-CoA acetyltransferase, mitochondrial; acetyl-Coenzyme A acetyltransferase 1; mitochondrial acetoacetyl-CoA thiolase; T2; testicular tissue protein Li 198
基因别名: 6330585C21Rik; ACAT; ACAT1; MAT; RATACAL; T2; THIL
UniProt ID: (Human) P24752, (Rat) P17764, (Mouse) Q8QZT1
Entrez Gene ID: (Human) 38, (Rat) 25014, (Mouse) 110446
acetyl-CoA C-acetyltransferase activity
enzyme binding
protein homodimerization activity
metal ion binding
coenzyme binding
catalytic activity
transferase activity
transferase activity, transferring acyl groups
transferase activity, transferring acyl groups other than amino-acyl groups
acyltransferase
liver development
brain development
branched-chain amino acid catabolic process
response to hormone
response to organic cyclic compound
response to starvation
ketone body biosynthetic process
ketone body catabolic process
protein homooligomerization
adipose tissue development
metanephric proximal convoluted tubule development
metabolic process
