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Immunogen sequence: MSSPQAPEDG QGCGDRGDPP GDLRSVLVTT VLNLEPLDED LFRGRHYWVP AKRLFGGQIV GQALVAAAKS VSEDVHVHSL HCYFVRAGDP KLPVLYQVER TRTGSSFSVR SVKAVQHGKP IFICQASFQQ AQPSPMQHQF SMPTVPPPEE LLDCETLIDQ YLRDPNLQKR YPLALNRIAA QEVPIEIKPV NPSPLSQLQR MEPKQMFWVR ARGYIGEGDM; Positive Samples: Jurkat, Raji, U-87MG, HeLa; Cellular Location: Peroxisome
Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. It may mediate Nef-induced down-regulation of CD4. It may be involved in the metabolic regulation of peroxisome proliferation.
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仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Acyl-CoA thioesterase 8; Acyl-coenzyme A thioesterase 8; choloyl-CoA hydrolase; Choloyl-coenzyme A thioesterase; hACTE-III; HIV-Nef associated acyl-CoA thioesterase; HIV-Nef-associated acyl-CoA thioesterase; long-chain fatty-acyl-CoA hydrolase; Nef (lentivirus myristoylated factor) associated protein 1; palmitoyl-CoA hydrolase; peroxisomal acyl-CoA thioesterase 1; Peroxisomal acyl-CoA thioesterase 2; Peroxisomal acyl-coenzyme A thioester hydrolase 1; Peroxisomal long-chain acyl-CoA thioesterase 1; PTE-1; PTE-2; Thioesterase II; thioesterase III
基因别名: ACOT8; ACTEIII; hACTE-III; HNAACTE; hTE; NAP1; PTE-1; PTE-2; PTE1; PTE2
UniProt ID: (Human) O14734
Entrez Gene ID: (Human) 10005
分子生物学功能:
esterase