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Immunogen sequence: AVRHQSEIKP GEPEPQILDF QTQQYKLFPL LATAYAFQFV GAYMKETYHR INEGIGQGDL SELPELHALT AGLKAFTSWT ANTGIEACRM ACGGHGY
The protein encoded by this gene is the first enzyme of the fatty acid beta-oxidation pathway, which catalyzes the desaturation of acyl-CoAs to 2-trans-enoyl-CoAs. It donates electrons directly to molecular oxygen, thereby producing hydrogen peroxide. Defects in this gene result in pseudoneonatal adrenoleukodystrophy, a disease that is characterized by accumulation of very long chain fatty acids. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: acyl-CoA oxidase 1, palmitoyl; acyl-CoA oxidase, straight-chain; acyl-Coenzyme A oxidase 1, palmitoyl; AOX; Palmitoyl-CoA oxidase; Peroxisomal acyl-coenzyme A oxidase 1; Peroxisomal fatty acyl-CoA oxidase; SCOX; Straight-chain acyl-CoA oxidase
基因别名: ACOX; ACOX1; PALMCOX; SCOX
UniProt ID: (Human) Q15067
Entrez Gene ID: (Human) 51