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产品信息
22214-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACP1 Fusion Protein Ag17539 (15-102 aa encoded by BC007422)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: GNICRSPIA EAVFRKLVTD QNISENWVID SGAVSDWNVG RSPDPRAVSC LRNHGIHTAH KARQITKEDF ATFDYILCMD ESNLRDLNR (15-102 aa encoded by BC007422)
靶标信息
Low molecular weight protein tyrosine phosphtases, including the human red cell phosphatase, HCPTP, are widely expressed cytosolic proteins of approximately 18 kDa that exist in distinct isoforms and are highly selective for phosphotyrosine over phosphoserine or phosphotyrosine. The HCPTP-A and HCPTP-B proteins expressed in human red cells and placenta are fast and slow forms of red cell acid phosphatase5. Like other tyrosine phosphatases, HCPTP is sensitive to inhibition by vanadate, and has a catalytic mechanism that involves formation of a cystinylphosphate intermediate6. The crystal structure of the bovine heart derived enzyme BHPTP shows a four-stranded central parallel b sheet with flanking a helices and an active site cysteine residue in the typical tyrosine phosphatase sequence context, CXXXXXR.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acid phosphatase of erythrocyte; Adipocyte acid phosphatase; cytoplasmic phosphotyrosyl protein phosphatase; HAAP betaÊ; LMW-PTP; LMW-PTPase; Low molecular weight cytosolic acid phosphatase; Low molecular weight phosphotyrosine protein phosphatase; MGC111030; MGC3499; protein tyrosine phosphatase; Red cell acid phosphatase 1; testicular secretory protein Li 37
基因别名: 4632432E04Rik; Acp-1; ACP1; AI427468; HAAP; LMW-PTP
UniProt ID: (Human) P24666, (Mouse) Q9D358
Entrez Gene ID: (Human) 52, (Mouse) 11431
