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产品信息
MA5-31548
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
GT186
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of Human FACL4.
偶联物
形式
Liquid
浓度
1.28 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2787176
产品详细信息
Keep as concentrated solution.
Predicted reactivity: Mouse (100%), Rat (100%), Pig (100%), Rhesus Monkey (100%).
Positive Control: HeLa.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: acyl-CoA synthetase 4; Arachidonate--CoA ligase; fatty acid-Coenzyme A ligase, long chain 4; fatty-acid-Coenzyme A ligase, long-chain 4; L MRX63; LACS 4; lignoceroyl-CoA synthase; Long-chain acyl-CoA synthetase 4; long-chain fatty-acid-Coenzyme A ligase 4; Long-chain-fatty-acid--CoA ligase 4; mACS4
基因别名: 9430020A05Rik; ACS4; ACSL4; AU018108; FACL4; LACS4; MRX63; MRX68
UniProt ID: (Human) O60488, (Mouse) Q9QUJ7
Entrez Gene ID: (Human) 2182, (Mouse) 50790
long-chain fatty acid metabolic process
lipid metabolic process
triglyceride metabolic process
response to nutrient
fatty acid transport
long-chain fatty-acyl-CoA biosynthetic process
embryonic process involved in female pregnancy
dendritic spine development
response to interleukin-15
fatty acid metabolic process
metabolic process
lipid biosynthetic process
regulation of fatty acid metabolic process
neuron differentiation
positive regulation of cell growth
negative regulation of prostaglandin secretion
