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产品信息
13537-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Not Applicable
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
ACTL7B Fusion Protein Ag4460 (1-415 aa encoded by BC033789)
偶联物
形式
Liquid
浓度
0.21 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MATRNSPMP LGTAQGDPGE AGTRPGPDAS LRDTGAATQL KMKPRKVHKI KAVIIDLGSQ YCKCGYAGEP RPTYFISSTV GKRCPEAADA GDTRKWTLVG HELLNTEAPL KLVNPLKHGI VVDWDCVQDI WEYIFRTAMK ILPEEHAVLV SDPPLSPSSN REKYAELMFE TFGIPAMHVT SQSLLSIYSY GKTSGLVVES GHGVSHVVPI SEGDVLPGLT SRADYAGGDL TNYLMQLLNE AGHAFTDDHL HIIEHIKKKC CYAAFLPEEE LGLVPEELRV DYELPDGKLI TIGQERFRCS EMLFQPSLAG STQPGLPELT AACLGRCQDT GFKEEMAANV LLCGGCTMLD GFPERFQREL SLLCPGDSPA VAAAPERKTS VWTGGSILAS LQAFQQLWVS KEEFEERGSV AIYSKC (1-415 aa encoded by B C033789)
靶标信息
The protein encoded by this gene is a member of a family of actin-related proteins which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene, and related gene, ACTL7A, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7B gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. Unlike ACTL7A, the ACTL7B gene is expressed predominantly in the testis, however, its exact function is not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: actin-like 7-beta; actin-like 7B; Actin-like protein 7B; Actin-like-7-beta; MGC151192; MGC151194; RP11-3J11.2; t-actin 1; T-actin-1; testis tissue sperm-binding protein Li 43a; Testis-specific actin-1
基因别名: ACTL7B; Tact1
UniProt ID: (Human) Q9Y614, (Mouse) Q9QY83, (Rat) Q4QR76
Entrez Gene ID: (Human) 10880, (Mouse) 11471, (Rat) 313183
