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产品信息
PA5-139814
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2926816
产品详细信息
Gently mix before use. Optimal concentrations and conditions for each application should be determined by the user.
Immunogen sequence: RYGSQLAPET FYRECDMQLF GPWGEIVSPS LSPATSNAGG CRLFINVAPH ARIAIHALAT NMGAGTEGAN ASYILIRDTH SLRTTAFHGQ QV
靶标信息
ADAMTS13 is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 13; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 13; ADAM-TS 13; ADAMs; metalloendopeptidases; von Willebrand factor-cleaving protease; vWF-cleaving protease; vWF-CP
基因别名: ADAM-TS13; ADAMTS-13; ADAMTS13; C9orf8; UNQ6102/PRO20085; vWF-CP; VWFCP
UniProt ID: (Human) Q76LX8
Entrez Gene ID: (Human) 11093
proteolysis
cell-matrix adhesion
integrin-mediated signaling pathway
glycoprotein metabolic process
response to toxic substance
protein processing
platelet activation
response to interferon-gamma
response to tumor necrosis factor
protein O-linked fucosylation
peptide catabolic process
response to interleukin-4
