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Immunogen sequence: KPDGANLRQR SAQQAGSKTV RLVTVPSSPP TKRVHLSSAS QMAAASFFAA SDSIGASSQA RTSKKDGKII D^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 48%, Rat - 30%.
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: a disintegrin and metalloproteinase; A disintegrin and metalloproteinase with thrombospondin motifs 3; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAM; ADAM metallopeptidase with thrombospondin type 1 motif, 3; ADAM-TS 3; ADAM-TS3; ADAMs; ADAMTS-3; metalloendopeptidases; PC II-NP; Procollagen II amino propeptide-processing enzyme; Procollagen II N-proteinase; zinc metalloendopeptidase
基因别名: ADAMTS-4; ADAMTS3; KIAA0366
UniProt ID: (Human) O15072
Entrez Gene ID: (Human) 9508