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产品信息
H00000108-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
1D4
抗原
ADCY2 (NP_065433, 977 a.a. approximately 1086 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: GKLDAINKHS FNDFKLRVGI NHGPVIAGVI GAQKPQYDIW GNTVNVASRM DSTGVLDKIQ VTEETSLVLQ TLGYTCTCRG IINVKGKGDL KTYFVNTEMS RSLSQSNVAS
靶标信息
ADCY2 is a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate(cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 3',5'-cyclic AMP synthetase; adenylate cyclase 2 (brain); adenylate cyclase II; Adenylate cyclase type 2; Adenylate cyclase type II; Adenylyl cyclase 2; ATP pyrophosphate-lyase 2; type II adenylate cyclase
基因别名: AC2; ADCY2; HBAC2; KIAA1060
UniProt ID: (Human) Q08462
Entrez Gene ID: (Human) 108
renal water homeostasis
cAMP biosynthetic process
adenylate cyclase-modulating G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
activation of adenylate cyclase activity
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
cAMP-mediated signaling
activation of protein kinase A activity
cellular response to glucagon stimulus
cellular response to forskolin
