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Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: AC8; adenylate cyclase 8 (brain); Adenylate cyclase type 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; adenylyl cyclase-8, brain; ATP pyrophosphate-lyase 8; Ca(2+)/calmodulin-activated adenylyl cyclase; epididymis secretory sperm binding protein Li 172mP; HEL-S-172mP; type VIII adenylyl cyclase
基因别名: AC8; ADCY3; ADCY8; AW060868; HBAC1
UniProt ID: (Human) P40145, (Rat) P40146, (Mouse) P97490
Entrez Gene ID: (Human) 114, (Rat) 29241, (Mouse) 11514