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Positive test controls include: HepG2, NIH/3T3, Mouse brain, Rat heart. The target is usually found in the following locations: Membrane, Peripheral membrane protein.
Immunogen sequence: MMQLVSSGVE NALTKSELLV EQYLPLTEEE LEKEAKKVEG FDLVQKPSYY VRLGSLSTKL HSRAYQQALS RVKEAKQKSQ QTISQLHSTV HLIEFARKNV YSANQKIQDA QDKLYLSWVE WKRSIGYDDT DESHCAEHIE SRTLAIARNL TQQLQTTCHT LLSNIQGVPQ NIQDQAKHMG VMAGDIYSVF RNAASFKEVS DSLLTSSKGQ LQKMKESLDD VMDYLVNNTP LNWLVGPFYP QLTESQNAQD QGAEMDKSSQ ETQRSEHKTH
Milk lipid globules from humans, cows and rats contain a protein identified as adipocyte differentiation-related protein (ADFP). It is associated with the globule surface membrane material. This protein, previously believed to be specific to adipocytes, is a major constituent of the globule surface and is present in a detergent-insoluble complex that contains butyrophilin and xanthine oxidase. ADFP (Adipophilin) is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells. In tissues, however, expression of adipophilin is restricted to specific cell types, such as lactating mammary epithelial cells, adrenal cortex cells, Sertoli and Leydig cells of the male reproductive system, and steatosis or fatty change hepatocytes in alcoholic liver cirrhosis. ADFP may be a possible new marker for the identification of specialized differentiated cells containing lipid droplets and for diseases associated with fat-accumulating cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Adipophilin; adipose differentiation related protein; Adipose differentiation-related protein; ADRP; ADRP antibody; MGC10598; Perilipin-2
基因别名: AA407157; ADFP; ADPH; ADRP; PLIN2
UniProt ID: (Human) Q99541, (Mouse) P43883
Entrez Gene ID: (Human) 123, (Mouse) 11520, (Rat) 298199