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Positive control: Chronic lymphocytic leukemia
Cellular location: Nucleus.
This gene encodes a RNA-editing deaminase that is a member of the cytidine deaminase family. The protein is involved in somatic hypermutation, gene conversion, and class-switch recombination of immunoglobulin genes. Defects in this gene are the cause of autosomal recessive hyper-IgM immunodeficiency syndrome type 2 (HIGM2).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Activation-induced cytidine deaminase; AID; Cytidine aminohydrolase; epididymis secretory protein Li 284; integrated into Burkitt's lymphoma cell line Ramos; Single-stranded DNA cytosine deaminase
基因别名: AICDA; AID; ARP2; CDA2; HEL-S-284; HIGM2
UniProt ID: (Human) Q9GZX7
Entrez Gene ID: (Human) 57379