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AK3 Antibody (CF501835) in WB
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY AK3 (RC204408, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-AK3. Positive lysates LY414079 (100 µg) and LC414079 (20 µg) can be purchased separately from OriGene.
产品信息
CF501835
产品规格
种属反应
Dog,
Human,
Rat
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
OTI6B7
抗原
Full length human recombinant protein of human AK3 produced in HEK293T cell.
偶联物
形式
Lyophilized
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 8% trehalose
内含物
no preservative
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
For reconstitution, we recommend adding 100 µL distilled water to a final antibody concentration of about 1 mg/mL. To use this carrier-free antibody for conjugation experiments, we strongly recommend performing another round of desalting. (Zeba Spin Desalting Columns, 7KMWCO, 0.5 mL, Product # 89882)
靶标信息
This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adenylate kinase 3; Adenylate kinase 3 alpha-like 1; adenylate kinase 3 alpha-like 1 {ECO:0000255|HAMAP-Rule:MF_03169}; adenylate kinase 3 {ECO:0000255|HAMAP-Rule:MF_03169}; adenylate kinase 6, adenylate kinase 3 like 1; Adenylate kinase isozyme 3; AK 3 {ECO:0000255|HAMAP-Rule:MF_03169}; AK3; AK4; GTP:AMP phosphotransferase AK3, mitochondrial; GTP:AMP phosphotransferase AK3, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03169}; GTP:AMP phosphotransferase mitochondrial; GTP:AMP phosphotransferase, mitochondrial
基因别名: AK3; AK3L1; AK6; AKL3L; AKL3L1; FIX
UniProt ID: (Human) Q9UIJ7, (Rat) P29411
Entrez Gene ID: (Human) 50808, (Dog) 476342, (Rat) 26956
ADP biosynthetic process
blood coagulation
phosphorylation
AMP metabolic process
GTP metabolic process
ITP metabolic process
UTP metabolic process
liver development
AMP phosphorylation
muscle organ development
cerebellum development
olfactory bulb development
response to starvation
ATP metabolic process
dATP metabolic process
nucleotide phosphorylation
protein homooligomerization
