Product References
Inceptor as a regulator of brain insulin sensitivity.
Scientific reports
Post LA,Kulas JA,Milstein JL,Sebastian SVL,Hosseini-Barkooie S,Stevenson ME,Bloom GS,Ferris HA
AHO1112 was used in Western Blotting to study Inceptor in healthy and diseased nervous tissue to understand the distribution of the protein and examine how it may change in states of insulin resistance.
Tue Jul 18 00:00:00 EDT 2023
Cancer-associated fibroblast-derived exosomal microRNA-20a suppresses the PTEN/PI3K-AKT pathway to promote the progression and chemoresistance of non-small cell lung cancer.
Clinical and translational medicine
Shi L,Zhu W,Huang Y,Zhuo L,Wang S,Chen S,Zhang B,Ke B
Published figure using AKT1 monoclonal antibody (Product # AHO1112) in Western Blot
Fri Jul 01 00:00:00 EDT 2022
Focal Adhesion Kinase Provides a Collateral Vulnerability That Can Be Leveraged to Improve mTORC1 Inhibitor Efficacy.
Cancers
Cuellar-Vite L,Weber-Bonk KL,Abdul-Karim FW,Booth CN,Keri RA
AHO1112 was used in Immunohistochemistry (Paraffin), Western Blot to reveal an innate dependency on FAK when mTORC1 signaling is lost in tumors that are resistant to mTORC1 inhibitors.
Mon Jul 11 00:00:00 EDT 2022
In Vitro Wound Healing Potential of Photobiomodulation Is Possibly Mediated by Its Stimulatory Effect on AKT Expression in Adipose-Derived Stem Cells.
Oxidative medicine and cellular longevity
Rajendran NK,Houreld NN,Abrahamse H
Published figure using AKT1 monoclonal antibody (Product # AHO1112) in Immunocytochemistry
Tue Sep 14 00:00:00 EDT 2021
Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis.
Cell reports
Duan S,Moro L,Qu R,Simoneschi D,Cho H,Jiang S,Zhao H,Chang Q,de Stanchina E,Arbini AA,Pagano M
AHO1112 was used in Immunohistochemistry (Paraffin), Western Blot to highlight the relevance of the FBXO31-DUSP6 axis in the regulation of ERK- and PI3K-AKT-mediated signaling pathways, as well as its therapeutic potential in prostate cancer.
Tue Oct 19 00:00:00 EDT 2021
Loss of FBXO31-mediated degradation of DUSP6 dysregulates ERK and PI3K-AKT signaling and promotes prostate tumorigenesis.
Cell reports
Duan S,Moro L,Qu R,Simoneschi D,Cho H,Jiang S,Zhao H,Chang Q,de Stanchina E,Arbini AA,Pagano M
AHO1112 was used in Immunohistochemistry (Paraffin), Western Blot to highlight the relevance of the FBXO31-DUSP6 axis in the regulation of ERK- and PI3K-AKT-mediated signaling pathways, as well as its therapeutic potential in prostate cancer.
Tue Oct 19 00:00:00 EDT 2021
Pooled screening for antiproliferative inhibitors of protein-protein interactions.
Nature chemical biology
Nim S,Jeon J,Corbi-Verge C,Seo MH,Ivarsson Y,Moffat J,Tarasova N,Kim PM
AHO1112 was used in western blot to assess antiproliferative inhibitors of protein-protein interactions by pooled screening
Fri Apr 01 00:00:00 EDT 2016
Regulation of H-Ras-driven MAPK signaling, transformation and tumorigenesis, but not PI3K signaling and tumor progression, by plasma membrane microdomains.
Oncogenesis
Michael JV,Wurtzel JG,Goldfinger LE
AHO1112 was used in western blot to define the contribution of the plasma membrane microdomain to the functions of H-Ras and R-Ras
Mon May 30 00:00:00 EDT 2016