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Invitrogen
ALDH1A1 Monoclonal Antibody (5G9E6C9)
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
图: 1 / 7
ALDH1A1 Antibody (MA5-29023) in ICC/IF
Immunofluorescence staining of Human ALDH1A1 in MCF7 or SKBR3 cells. Cells were fixed with 4% PFA, permeabilzed with 1% Triton X-100 in PBS, blocked with 10% serum, and incubated with ALDH1A1 Monoclonal Antibody (5G9E6C9) (Product # MA5-29023, 1:60). Then cells were stained with the Alexa Fluor® 488-conjugated Goat Anti-mouse IgG secondary antibody (left panel, captured by laser confocal scanning microscope; right panel, captured by fluorescence microscope), counterstained with DAPI (blue). Positive staining was localized to cytoplasm.
产品信息
MA5-29023
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
已发表种属
Not Applicable
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
5G9E6C9
抗原
Recombinant Human ALDH1 protein (Ser2-Ser501)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2784960
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human ALDH1/ALDH1A1/ALDC.
靶标信息
ALDH1A1 belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50% of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 3-deoxyglucosone dehydrogenase; acetaldehyde dehydrogenase 1; aldehyde dehydrogenase 1 family, member A1; Aldehyde dehydrogenase 1 soluble; aldehyde dehydrogenase 1, soluble; Aldehyde dehydrogenase 1A1; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic; aldehyde dehydrogenase, liver cytosolic; ALDH class 1; ALDH-E1; ALHDII; epididymis luminal protein 12; epididymis luminal protein 9; epididymis secretory sperm binding protein Li 53e; epididymis secretory sperm binding protein Li53e; MGC2318; RALDH 1; Retinal dehydrogenase 1; retinaldehyde dehydrogenase 1
基因别名: ALDC; ALDH-E1; ALDH1; ALDH11; ALDH1A1; HEL-9; HEL-S-53e; HEL12; PUMB1; RALDH1
UniProt ID: (Human) P00352
Entrez Gene ID: (Human) 216
