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产品信息
PA5-50315
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to a region derived from internal residues of human aldehyde dehydrogenase 8 family, member A1
偶联物
形式
Liquid
浓度
1.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2635768
产品详细信息
The antibody detects endogenous levels of total ALDH8A1 protein.
靶标信息
This protein belongs to the aldehyde dehydrogenases family of proteins. It plays a role in a pathway of 9-cis-retinoic acid biosynthesis in vivo. This enzyme converts 9-cis-retinal into the retinoid X receptor ligand 9-cis-retinoic acid, and has approximately 40-fold higher activity with 9-cis-retinal than with all-trans-retinal. Therefore, it is the first known aldehyde dehydrogenase to show a preference for 9-cis-retinal relative to all-trans-retinal. Two transcript variants encoding distinct isoforms have been identified for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2-aminomuconic semialdehyde dehydrogenase; Aldehyde dehydrogenase 12; aldehyde dehydrogenase 8 family, member A1; Aldehyde dehydrogenase family 8 member A1; aldehyde dehydrogenase family protein; Retinal dehydrogenase 4; retinal dehydrogenase type 4
基因别名: ALDH12; ALDH8A1; DJ352A20.2; Raldh4
UniProt ID: (Human) Q9H2A2, (Mouse) Q8BH00
Entrez Gene ID: (Human) 64577, (Mouse) 237320
retinal dehydrogenase activity
aldehyde dehydrogenase (NAD) activity
3-chloroallyl aldehyde dehydrogenase activity
oxidoreductase activity
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
1-hydroxy-2-naphthaldehyde dehydrogenase activity
cis-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
2-carboxybenzaldehyde dehydrogenase activity
trans-2-methyl-5-isopropylhexa-2,5-dienal dehydrogenase activity
benzaldehyde dehydrogenase activity
2-naphthaldehyde dehydrogenase activity
1-naphthaldehyde dehydrogenase activity
4-hydroxymethylsalicyaldehyde dehydrogenase activity
3-methylsalicylaldehyde dehydrogenase activity
oxoglutarate dehydrogenase [NAD(P)+] activity
oxoglutarate dehydrogenase (NAD+) activity
pyruvate dehydrogenase [NAD(P)+] activity
pyruvate dehydrogenase (NAD+) activity
citronellal dehydrogenase activity
geranial dehydrogenase activity
N2-acetyl-L-aminoadipate semialdehyde dehydrogenase activity
glyceraldehyde dehydrogenase (NADP) activity
N-acetyl-gamma-aminoadipyl-phosphate reductase activity
glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity
2,5-dioxovalerate dehydrogenase (NAD+) activity
medium-chain-aldehyde dehydrogenase activity
dehydrogenase
