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ALOX12 Antibody (PA5-97455) in ICC/IF
Immunofluorescent analysis of ALOX12 in A549 cells using a ALOX12 polyclonal antibody (Product # PA5-97455) at a dilution of 1:166. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated Goat Anti-Rabbit IgG(H+L). Cells were counter-stained with DAPI.
产品信息
PA5-97455
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human Arachidonate 12-lipoxygenase, 12S-type protein (508-658AA)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein G
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.03% ProClin 300
保存条件
-20°C or -80°C if preferred
运输条件
Wet ice
RRID
AB_2812072
靶标信息
Oxygenase and 14,15-leukotriene A4 synthase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 12(S)-lipoxygenase; 12LOX; 12S LOX; 12S-lipoxygenase; 12S-LOX; Arachidonate (12S)-lipoxygenase; Arachidonate (15S)-lipoxygenase; arachidonate 12-lipoxygenase; Linoleate (13S)-lipoxygenase; Lipoxin synthase 12-LO; platelet 12-LOX; platelet-type 12-lipoxygenase; Platelet-type lipoxygenase 12; Polyunsaturated fatty acid lipoxygenase ALOX12
基因别名: 12-LOX; 12LO; 12S-LOX; ALOX12; LOG12
UniProt ID: (Human) P18054
Entrez Gene ID: (Human) 239
arachidonate 12-lipoxygenase activity
iron ion binding
protein binding
linoleate 13S-lipoxygenase activity
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
hepoxilin-epoxide hydrolase activity
hepoxilin A3 synthase activity
oxygenase
movement of cell or subcellular component
aging
positive regulation of cell proliferation
positive regulation of endothelial cell migration
positive regulation of gene expression
negative regulation of muscle cell apoptotic process
arachidonic acid metabolic process
lipoxygenase pathway
fatty acid oxidation
positive regulation of cell growth
positive regulation of cell migration
superoxide anion generation
negative regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
linoleic acid metabolic process
positive regulation of endothelial cell differentiation
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of vasodilation
positive regulation of smooth muscle cell proliferation
hepoxilin metabolic process
hepoxilin biosynthetic process
positive regulation of mitochondrial depolarization
establishment of skin barrier
cellular response to lipid
reactive oxygen species metabolic process
negative regulation of platelet aggregation
leukotriene A4 metabolic process
lipoxin metabolic process
lipoxin A4 biosynthetic process
lipoxin B4 biosynthetic process
