Target of Interest
Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
67182-1-IG
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
1E11D4
抗原
PRKAG1 Fusion Protein Ag28907
偶联物
Unconjugated
形式
Liquid
浓度
1000 µg/mL
纯化类型
Protein G
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Aliquoting is unnecessary for -20°C storage.
靶标信息
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMP-activated protein kinase, noncatalytic gamma-1 subunit; ampk gamma; AMPK gamma-1 chain; AMPK gamma1; AMPK subunit gamma-1; AMPKg; Protein kinase AMP-activated gamma; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
基因别名: AA571379; AMPKG; BB036179; Prkaac; PRKAG1; Prkga1
UniProt ID: (Human) P54619, (Mouse) O54950, (Rat) P80385
Entrez Gene ID: (Human) 5571, (Mouse) 19082, (Rat) 25520
regulation of glycolytic process
protein phosphorylation
fatty acid biosynthetic process
cell cycle arrest
signal transduction
spermatogenesis
positive regulation of gene expression
macroautophagy
positive regulation of protein kinase activity
regulation of signal transduction by p53 class mediator
lipid metabolic process
fatty acid metabolic process
regulation of catalytic activity
protein heterooligomerization
