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ANKS1B Antibody (PA5-121141) in WB
Western blot analysis of ANKS1B in extracts of various cell lines. Samples were incubated with ANKS1B Polyclonal antibody (Product # PA5-121141) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.
产品信息
PA5-121141
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 261-510 of human ANKS1B (NP_858056.2).
偶联物
Unconjugated
形式
Liquid
浓度
0.45 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
AB_2914713
产品详细信息
Positive test controls include: A-549, Mouse liver. The target is usually found in the following locations: Cajal body, Cell junction, Cell projection, Cytoplasm, Nucleus, dendritic spine, postsynaptic cell membrane, postsynaptic density, synapse.
Immunogen sequence: GFPFSAIHQV HNTGDWGEPS ITLRPPNEAT ASTPVQYWQH HPEKLIFQSC DYKAFYLGSM LIKELRGTES TQDACAKMRA NCQKSTEQMK KVPTIILSVS YKGVKFIDAT NKNIIAEHEI RNISCAAQDP EDLSTFAYIT KDLKSNHHYC HVFTAFDVNL AYEIILTLGQ AFEVAYQLAL QARKGGHSST LPESFENKPS KPIPKPRVSI RKSVQIDPSE QKTLANLPWI VEPGQEAKRG INTKYETTIF
靶标信息
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization) have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: AIDA-1; amyloid-beta precursor protein intracellular domain associated protein 1; Amyloid-beta protein intracellular domain-associated protein 1; Ankyrin repeat and sterile alpha motif domain-containing protein 1B; cajalin 2; E2A-PBX1-associated protein; EB-1; MGC26087
基因别名: AIDA; AIDA-1; AIDA-1b; ANKS1B; ANKS2; C030032C09Rik; cajalin-2; E530015N03Rik; EB-1; EB1; ENSMUSG00000078431; Gm10937; Gm1555; RGD1565556
UniProt ID: (Human) Q7Z6G8, (Mouse) Q8BIZ1
Entrez Gene ID: (Human) 56899, (Mouse) 77531, (Rat) 314721
