Proteintech

ANT1/2 Polyclonal Antibody

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ANT1/2 Antibody (15997-1-AP) in WB

Mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 15997-1-AP (ANT1/2antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

ANT1/2 Antibody in Immunoprecipitation (IP)

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产品信息

15997-1-AP

应用

建议稀释比

已发表文章

免疫印迹 (WB)

1:500-1:1,000

查看4篇已发表文章 4篇已发表文章

免疫沉淀 (IP)

0.5-4.0 µg

查看1篇已发表文章 1篇已发表文章

其他PubMed (Misc)

查看1篇已发表文章 1篇已发表文章

产品规格

种属反应

Human, Mouse, Rat

已发表种属

Mouse

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

ANT1/2 Fusion Protein Ag7787 (1-298 aa encoded by BC008664)

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.33 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.3, with 50% glycerol

内含物

0.02% sodium azide

保存条件

-20°C

运输条件

Wet ice (domestic); Dry ice (international)

产品详细信息

This antibody recognizes both of ANT1 and ANT2.

Immunogen sequence: MGDHAWSFL KDFLAGGVAA AVSKTAVAPI ERVKLLLQVQ HASKQISAEK QYKGIIDCVV RIPKEQGFLS FWRGNLANVI RYFPTQALNF AFKDKYKQLF LGGVDRHKQF WRYFAGNLAS GGAAGATSLC FVYPLDFART RLAADVGKGA AQREFHGLGD CIIKIFKSDG LRGLYQGFNV SVQGIIIYRA AYFGVYDTAK GMLPDPKNVH IFVSWMIAQS VTAVAGLVSY PFDTVRRRMM MQSGRKGADI MYTGTVDCWR KIAKDEGAKA FFKGAWSNVL RGMGGAFVLV LYDEIKKYV (1-298 aa encoded by BC008664 )

靶标信息

Adenine nucleotide translocator (ANT) and the voltage-dependent anion-selective channel proteins 1 and 2 (VDAC1 and VDAC2) are components of the permeability transition pore complex (PTPC) of the mitochondrial inner and outer membranes, respectively. Formation of PTPCs, the subsequent dissipation of mitochondrial inner membrane potential and release of cytochrome c through the outer mitochondrial membrane are critical events in the early stages of apoptosis. Bax, a proapoptotic protein, has been shown to act upon ANT to induce the dissipation of mitochondrial inner membrane potential. ANT1 has a role in the maintenance of mitochondrial DNA by catalyzing the exchange of ADP and ATP across the mitochondrial inner membrane.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

Product References

Deregulation of ER-mitochondria contact formation and mitochondrial calcium homeostasis mediated by VDAC in fragile X syndrome.

Developmental cell

Geng J,Khaket TP,Pan J,Li W,Zhang Y,Ping Y,Cobos Sillero MI,Lu B

Mon Apr 10 00:00:00 EDT 2023

MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.

iScience

Ji X,Chu L,Su D,Sun J,Song P,Sun S,Wang Y,Mu Q,Liu Y,Wan Q

Fri May 19 00:00:00 EDT 2023

MRPL12-ANT3 interaction involves in acute kidney injury via regulating MPTP of tubular epithelial cells.

iScience

Ji X,Chu L,Su D,Sun J,Song P,Sun S,Wang Y,Mu Q,Liu Y,Wan Q

Fri May 19 00:00:00 EDT 2023

A new circular RNA-encoded protein BIRC6-236aa inhibits transmissible gastroenteritis virus (TGEV)-induced mitochondrial dysfunction.

The Journal of biological chemistry

Zhao X,Guo J,Wang X,Lin J,Liu Z,Xu C,Zhang D,Tong D

Thu Sep 01 00:00:00 EDT 2022

Regulation of DNA demethylation by the XPC DNA repair complex in somatic and pluripotent stem cells.

Genes & development

Ho JJ,Cattoglio C,McSwiggen DT,Tjian R,Fong YW

Sat Apr 15 00:00:00 EDT 2017

Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8.

Neurochemistry international

Eckert GP,Schiborr C,Hagl S,Abdel-Kader R,Müller WE,Rimbach G,Frank J

Mon Apr 01 00:00:00 EDT 2013

Curcumin prevents mitochondrial dysfunction in the brain of the senescence-accelerated mouse-prone 8.

Neurochemistry international

Eckert GP,Schiborr C,Hagl S,Abdel-Kader R,Müller WE,Rimbach G,Frank J

Mon Apr 01 00:00:00 EDT 2013

生物信息学

蛋白别名: Adenine nucleotid translocator 2 fibroblast isoform (ATP-ADP carrier protein); Adenine nucleotid translocator 2, fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocase-1; Adenine nucleotide translocator 1; adenine nucleotide translocator 1 (skeletal muscle); adenine nucleotide translocator 1, skeletal muscle; Adenine nucleotide translocator 2; adenine nucleotide translocator 2 (fibroblast); adenine nucleotide translocator 2 fibroblast isoform (ATP-ADP carrier protein); adenine nucleotide translocator 2, fibroblast isoform (ATP-ADP carrier protein); ADP,ATP carrier protein 1; ADP,ATP carrier protein 2; ADP,ATP carrier protein, fibroblast isoform; ADP,ATP carrier protein, heart/skeletal muscle; ADP,ATP carrier protein, heart/skeletal muscle isoform T1; ADP/ATP translocase 1; ADP/ATP translocase 2; ANT 1; ANT 2; heart/skeletal muscle ATP/ADP translocator; mANC1; mitochondrial adenine nucleotide translocator; solute carrier family 25 (mitochondrial adenine nucleotide translocator) member 4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Solute carrier family 25 member 4; Solute carrier family 25 member 5

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基因别名: 2F1; AAC1; AAC2; Anc1; ANT; ANT 1; ANT1; ANT2; AU019225; MTDPS12; PEO2; PEO3; PEOA2; SLC25A4; SLC25A5; T1; T2; T3