Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-69361
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the middle region of human AOC2
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2688935
产品详细信息
This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 83%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 92%; Rabbit: 100%; Rat: 83%
靶标信息
Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. [provided by RefSeq].
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Amine oxidase [copper-containing] 2; amine oxidase copper containing 2; Amine oxidase copper-containing 2; amine oxidase, copper containing 2 (retina-specific); RAO; Retina-specific copper amine oxidase; Semicarbazide-sensitive amine oxidase; SSAO
基因别名: AOC2; DAO2; RAO
UniProt ID: (Human) O75106
Entrez Gene ID: (Human) 314
copper ion binding
primary amine oxidase activity
electron carrier activity
quinone binding
tryptamine:oxygen oxidoreductase (deaminating) activity
aminoacetone:oxygen oxidoreductase(deaminating) activity
aliphatic-amine oxidase activity
phenethylamine:oxygen oxidoreductase (deaminating) activity
oxidase
