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AP2 gamma Antibody (PA5-116030) in IHC (P)
Immunohistochemistry analysis of AP2 gamma in rat brain tissue. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-116030) at a dilution of 1:100. Secondary staining was applied with HRP conjugated goat anti-rabbit.
产品信息
PA5-116030
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human TFAP2C(Accession Q92754), corresponding to amino acid residues V409-K450.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2900664
产品详细信息
Antibody detects endogenous levels of total TFAP2C.
靶标信息
The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: activating enhancer binding protein 2 gamma; Activating enhancer-binding protein 2 gamma; activator protein 2 gamma; AP2-gamma; estrogen receptor factor 1; Transcription factor AP-2 gamma; transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma); transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma); Transcription factor ERF-1
基因别名: AP2-GAMMA; ERF1; hAP-2g; Tcfap2c; TFAP2C; TFAP2G
UniProt ID: (Human) Q92754
Entrez Gene ID: (Human) 7022, (Rat) 362280
RNA polymerase II regulatory region sequence-specific DNA binding
core promoter binding
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
protein binding
protein dimerization activity
RNA polymerase II distal enhancer sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
molecular_function
general transcription factor
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
cell-cell signaling
male gonad development
regulation of gene expression, epigenetic
regulation of cell proliferation
positive regulation of transcription from RNA polymerase II promoter
trophectodermal cell differentiation
hair follicle development
keratinocyte development
regulation of transcription, DNA-templated
biological_process
stem cell population maintenance
forebrain neuron fate commitment
cerebral cortex development
cell differentiation
germ-line stem cell population maintenance
somatic stem cell population maintenance
skin development
regulation of epidermis development
sebaceous gland development
anatomical structure development
dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis
epithelial cell proliferation involved in mammary gland duct elongation
