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产品信息
13177-1-AP
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
APBB2 Fusion Protein Ag3844 (386-736 aa encoded by BC027946)
偶联物
形式
Liquid
浓度
0.31 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: SCSINSDPE AKCFAVRSLG WVEMAEEDLA PGKSSVAVNN CIRQLSYCKN DIRDTVGIWG EGKDMYLILE NDMLSLVDPM DRSVLHSQPI VSIRVWGVGR DNGRDFAYVA RDKDTRILKC HVFRCDTPAK AIATSLHEIC SKIMAERKNA KALACSSLQE RANVNLDVPL QDFPTPKTEL VQKFHVQYLG MLPVDKPVGM DILNSAIENL MTSSNKEDWL SVNMNVADAT VTVISEKNEE EVLVECRVRF LSFMGVGKDV HTFAFIMDTG NQRFECHVFW CEPNAGNVSE AVQAACMLRY QKCLVARPPS QKVRPPPPPA DSVTRRVTTN VKRGVLSLID TLKQKRPVTE MP (386-736 aa encoded by BC027946)
靶标信息
The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta precursor protein and amyloid beta precursor-like protein 2. This protein contains two phosphotyrosine binding domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: amyloid beta (A4) precursor protein-binding, family B, member 2; amyloid beta A4 precursor protein-binding family B member 2; Amyloid beta precursor protein binding family B member 2; amyloid beta precursor protein-binding family B member 2; Amyloid-beta (A4) precursor protein-binding family B member 2; Fe65-like 1; Protein Fe65-like 1; zinc finger-like protein
基因别名: 2310007D03Rik; APBB2; FE65L; FE65L1; RGD1562438; Rirl1; TR2L; Zfra
UniProt ID: (Human) Q92870, (Mouse) Q9DBR4
Entrez Gene ID: (Human) 323, (Rat) 305338, (Mouse) 11787
neuron migration
regulation of transcription, DNA-templated
cell cycle arrest
axon guidance
biological_process
extracellular matrix organization
negative regulation of cell growth
positive regulation of apoptotic process
negative regulation of apoptotic process
intracellular signal transduction
actin filament-based movement
protein stabilization
