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Invitrogen
APOB48R Polyclonal Antibody
高级验证
This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated.
产品信息
PA5-59670
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.4 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2638080
产品详细信息
Immunogen sequence: EKWTLLEEEA VGWQEREQRE DSEGRCGDYH PEGEAPRLLD AEGLMVTGGR RAEAKETEPE SLEHVRGQEE QPTHQAPAEA APESVGEA
Highest antigen sequence identity to the following orthologs: Mouse - 30%, Rat - 34%.
靶标信息
Macrophage receptor that binds to the apolipoprotein B48 (APOB) of dietary triglyceride (TG)-rich lipoproteins (TRL) or to a like domain of APOB in hypertriglyceridemic very low density lipoprotein (HTG-VLDL). Binds and internalizes TRL when out of the context of the macrophage. May provide essential lipids to reticuloendothelial cells. Could also be involved in foam cell formation with elevated TRL and remnant lipoprotein (RLP). Mediates the rapid high-affinity uptake of chylomicrons (CM), HTG- VLDL, and trypsinized (tryp) VLDL devoid of APOE in vitro in macrophages.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: apoB-48R; Apolipoprotein B receptor; Apolipoprotein B-100 receptor; Apolipoprotein B-48 receptor; apolipoprotein B100 receptor; Apolipoprotein B48 receptor
基因别名: APOB100R; APOB48R; APOBR
UniProt ID: (Human) Q0VD83
Entrez Gene ID: (Human) 55911
