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APOBEC3D/APOBEC3F Antibody (PA5-101777) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded APOBEC3D/APOBEC3F in rat lung tissue. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with APOBEC3D/APOBEC3F polyclonal antibody (Product # PA5-101777) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-101777
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human APOBEC3D(Accession Q96AK3), corresponding to amino acid residues I41-R91.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2851209
产品详细信息
Antibody detects endogenous levels of total APOBEC3D/F.
靶标信息
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: A3F; apolipoprotein B editing enzyme catalytic polypeptide-like 3F; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D; apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3F; apolipoprotein B mRNA editing enzyme cytidine deaminase; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3E pseudogene; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F; Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like 3F; DNA dC->dU-editing enzyme APOBEC-3F; induced upon T-cell activation; probable DNA dC->dU-editing enzyme APOBEC-3D
基因别名: A3D; A3F; APOBEC3DE; APOBEC3E; APOBEC3F; ARP6; ARP8; BK150C2.4.MRNA; KA6
UniProt ID: (Human) Q8IUX4
Entrez Gene ID: (Human) 140564, (Human) 200316
negative regulation of transposition
innate immune response
negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
defense response to virus
DNA cytosine deamination
positive regulation of defense response to virus by host
cytidine deamination
base conversion or substitution editing
negative regulation of viral genome replication
negative regulation of viral process
DNA demethylation
