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Invitrogen
APPL1 Polyclonal Antibody
高级验证
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
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APPL1 Antibody (PA5-76172) in WB
Western blot was performed using Anti-APPL1 Rabbit Polyclonal Antibody (Product # PA5-76172) and a 79 kDa band corresponding to APPL1 was observed across cell lines and tissues tested. Whole cell extracts (30 µg lysate) of SW480 (Lane 1), MCF7 (Lane 2), HeLa (Lane 3), HEK-293 (Lane 4), Mouse Brain (Lane 5), Rat Brain (Lane 6) and Mouse Spleen (Lane 7) were electrophoresed using NuPAGE™ 4-12% Bis-Tris Protein Gel (Product # NP0322BOX). Resolved proteins were then transferred onto a nitrocellulose membrane (Product # IB23001) by iBlot® 2 Dry... View More
产品信息
PA5-76172
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein of human APPL1.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 50% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
AB_2719899
产品详细信息
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
靶标信息
The protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signaling and insulin signaling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Adapter protein containing PH domain, PTB domain and leucine zipper motif 1; adaptor protein APPL like; adaptor protein containing pH domain, PTB domain and leucine zipper motif 1; adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1; AKT2 interactor; DCC-interacting protein 13-alpha; DIP13 alpha; Dip13-alpha; signaling adaptor protein DIP13alpha
基因别名: 2900057D21Rik; 7330406P05Rik; AI585782; APPL; APPL1; AW209077; BB022931; C88264; DIP13; DIP13A; DIP13alpha; KIAA1428; MODY14; RGD1309388
UniProt ID: (Human) Q9UKG1, (Mouse) Q8K3H0
Entrez Gene ID: (Human) 26060, (Rat) 290537, (Mouse) 72993
