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产品信息
PA5-92354
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human ARL13B (NP_8788991)
偶联物
形式
Liquid
浓度
3.83 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.09% sodium azide
保存条件
-20° C, Avoid Freeze/Thaw Cycles
运输条件
Wet ice
RRID
AB_2806450
产品详细信息
Immunogen sequence: MFSLMASCCG WFKRWREPVR KVTLLMVGLD NAGKTATAKG IQGEYPEDVA PTVGFSKINL RQGKFEVTIF DLGGGIRIRG IWKNYYAESY GVIFVVDSSD EERMEETKEA MSEMLRHPRI SGKPILVLAN KQDKEGALGE ADVIECLSLE KLVNEHKCLC QIEPCSAISG YGKKIDKSIK KGLYWLLHVI ARDFDALNER IQKETTEQRA LEEQEKQERA ERVRKLREER KQNEQEQAEL; Positive Samples: SKOV3; Cellular Location: Cell projection, Lipid-anchor, cilium membrane
靶标信息
This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ADP-ribosylation factor like GTPase 13B; ADP-ribosylation factor-like 13B; ADP-ribosylation factor-like 2-like 1; ADP-ribosylation factor-like protein 13B; ADP-ribosylation factor-like protein 2-like 1; ARL2-like protein 1; Protein hennin
基因别名: A530097K21Rik; A930014M17Rik; ARL13B; ARL2L1; C530009C10Rik; hnn; JBTS8
UniProt ID: (Human) Q3SXY8, (Mouse) Q640N2
Entrez Gene ID: (Human) 200894, (Rat) 304037, (Mouse) 68146
heart looping
smoothened signaling pathway
small GTPase mediated signal transduction
dorsal/ventral pattern formation
neural tube patterning
interneuron migration from the subpallium to the cortex
formation of radial glial scaffolds
nonmotile primary cilium assembly
cilium assembly
left/right axis specification
determination of left/right symmetry
multicellular organism development
