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This target displays homology in the following species: Cow: 100%; Dog: 100%; Goat: 77%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 90%; Zebrafish: 100%
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This complex controls actin polymerization in cells and has been conserved throughout eukaryotic evolution. This gene encodes the p20 subunit, which is necessary for actin nucleation and high-affinity binding to F-actin. Alternative splicing results in multiple transcript variants. Naturally occurring read-through transcription exists between this gene and the downstream tubulin tyrosine ligase-like family, member 3, which results in the production of a fusion protein.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Actin-related protein 2/3 complex subunit 4; Arp2/3 complex 20 kDa subunit; MGC13544; p20-ARC
基因别名: 20kDa; 5330419I20Rik; AI327076; Arc20; Arpc4; p20-Arc
UniProt ID: (Mouse) P59999
Entrez Gene ID: (Mouse) 68089
分子生物学功能: actin or actin-binding cytoskeletal protein cytoskeletal protein