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Immunogen sequence: EVLDMADNA FDDEYLKCTD RMEIKYVPQL LKEEKASHQQ LDTVWENAKA KWAARKTQIF LPMNFKDNHG IALMAYISEA QEQTPFYHLF SEAVKMAGQS REDYIYGFQF KAFHFYLTRA LQLLRKPCEA SSKTVVYRTS QGTSFTFGGL NQARFGHFTL AYSAKPQAAN DQLTVLSIYT CLGVDIENFL DKESERITLI PLNEVFQVSQ EGAGNNLILQ SINKTCSHYE CAFLGGLKTE NCIENLEYFQ PIYVYNPGEK NQKLEDHSEK NWKLEDHGEK NQKLEDHGVK ILEPTQIPGM KIPEPFPLPE DKSQGNINNP TPGPVPVPGP KSHPSASLG (27-364 aa encoded by BC008397)
Mono-ADP-ribosylation involves the transfer of the ADP-ribose moiety from NAD+ to a specific amino acid in the target protein. The rodent mono-ADP-ribosyltransferase RT6 is a glycosylphosphatidylinositol (GPI)-anchored membrane protein specifically expressed at the cell surface of rat and mouse T lymphocytes. The predicted 367-amino acid human ART3 protein has an estimated molecular mass of 41.5 kD and contains a hydrophobic peptide signal at its N terminus, 3 consensus motifs specific to enzymes catalyzing ADP-ribose transfer, a hydrophobic C-terminal sequence characteristic of a GPI-anchored protein, a novel motif repeated 3 times at its C terminus, and 1 potential glycosylation site.1 The ART3 and rodent RT6 proteins share 35% amino acid identity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ADP-ribosyltransferase C2 and C3 toxin-like 3; ART3 mono(ADP-ribosyl)transferase; ARTC3; Ecto-ADP-ribosyltransferase 3; Mono(ADP-ribosyl)transferase 3; mono-ADP-ribosyltransferase; mono-ADP-ribosyltransferase 3; NAD(P)(+)--arginine ADP-ribosyltransferase 3
基因别名: 4930569O04Rik; ART3; ARTC3; TMART
UniProt ID: (Human) Q13508, (Mouse) Q8R2G4
Entrez Gene ID: (Human) 419, (Mouse) 109979, (Rat) 305235
分子生物学功能:
transferase