Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
产品信息
PA5-50361
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Fusion protein corresponding to a region derived from internal residues of human ankyrin repeat and SOCS box containing 2
偶联物
形式
Liquid
浓度
2.3 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 40% glycerol
内含物
0.05% sodium azide
保存条件
-20°C
运输条件
Wet ice
RRID
AB_2635814
产品详细信息
The antibody detects endogenous levels of total ASB2 protein.
靶标信息
The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. This gene is induced by all-trans retinoic acid. In myeloid leukemia cells, the expression of this encoded protein has been shown to induce growth inhibition and chromatin condensation. Multiple alternatively spliced transcript variants have been described for this gene but their full length sequences are not known.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: Ankyrin repeat and SOCS box protein 2; ankyrin repeat and SOCS box-containing protein 2a; ASB-2; MGC40044
基因别名: ASB-2; ASB2
UniProt ID: (Human) Q96Q27
Entrez Gene ID: (Human) 51676
protein polyubiquitination
positive regulation of defense response to virus by host
signal transduction
intracellular signal transduction
skeletal muscle cell differentiation
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
myoblast differentiation
mitophagy in response to mitochondrial depolarization
xenophagy
